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Factor Eleven: CranPlex



Urinary and bladder infections are usually caused by the bacterium Escherichia coli that results in cystitis, an inflammation of the bladder. Such infections are ten times more common in adult women than men. In fact, 21% of all women have urinary tract discomfort at least once a year, which may be extremely painful.1

Antibiotics losing effectiveness

Antibiotic (against life) resistance has become a concern for physicians who treat URI (urinary tract infections). Most women resort to expensive antibiotics which, according to a recent AMA study, quickly become ineffective as bacteria develop an immunity to them. In fact, Escherichia coli, can dodge antibiotics by invading the immune system cells lining the bladder wall. Furthermore, recent clinical data by the American Medical Association suggests that the three most commonly prescribed for URI (ampicillin, trimethoprim and trimetho-sulfamethoxazole) may not be acceptable choices for therapy much longer.2

CranPlex retains effectiveness

Cranberry (freeze-dried) has been shown in several clinical studies to be extremely effective in treating bladder infections.3.4. In one study, 16 ounces of cranberry juice per day was shown to produce beneficial effects in 73% of the subjects (44 females and 16 males) with active urinary tract infections.5

Cranberry's have the ability to prevent bladder infections due to the presence of the compound tannin which prevents bacteria from attaching to the inside surface of the lining within the urinary tract. This study also determined that tannin was only present in cranberries and blueberries.6

CranPlex contains freeze-dried cranberry, which prevents Escherichia coli bacterium from attaching to the cells that line the inside surface of the urinary tract and bladder. Unfortunately, most cranberry juice products are loaded with sugar, which acts to nullify the positive effect of cranberry. Cranberry juice in pill form is an excellent curative, as well as, preventive.

CranPlex also contains Goldenseal and Uva Ursi, two natural antibiotics that destroy infection-causing bacterium. Goldenseal's efficacy against numerous forms of E. coli bacteria is well documented in the scientific literature7 while Bearberry (Uva Ursi) has proven to have a powerful urinary antiseptic component and acts as a mild diuretic.8 Bearberry is reported to be especially active against E. coli.9

Freeze dried Aloe vera and Juniper berries balance out the CranPlex formulation. Aloe vera has demonstrated strong antibacterial properties and is an immune system stimulant. Compounds found in Aloe vera known as anthraquinones bind calcium in the urinary tract and significantly reduce the growth rate of urinary calcium crystals responsible for kidney stones.10 Juniper berries are particularly soothing to the kidneys and has been used in America for over 200 years as a urinary antiseptic.11

Why bladder infections keep reoccurring

Urinary and bladder infections have long baffled the medical professional and the agonized patients, with its resiliency. A strong dose of antibiotics usually brings immediate relief, but the painful infection often returns in as little as a few days. Recent research has discovered that the bacterium E. coli can dodge antibiotics by invading the immune system cells lining the wall of the bladder.12, thus E. coli can take shelter in the very cells that usually destroy them.

Pure cranberry juice (no sugar) or freeze dried cranberry in the quantity contained in Factor Eleven: CranPlex, prevents E. coli bacteria from attaching to the cells that line the inside surface of the urinary tract and bladder. Without the ability to invade these immune cells, the bacteria are flushed from the bladder during urination. One tablet of CranPlex contains the equivalent of 24 ounces of cranberry juice.

Recommendations to facilitate the immune system in fighting bladder and urinary tract infections:

  • Empty your bladder as often as possible ~ at least once every 3 hours ~ and empty it completely.
  • Empty bladder before and after both exercise and sexual intercourse to avoid undue strain.
  • Reduce/avoid intake of caffeinated drinks such as coffee, tea and colas. They tend to irritate the bladder.
  • Keep the genital and anal area clean and dry. Avoid hygiene spray, douches, and bubble baths as these may cause further irritations.
  • Take hot baths (sitz baths) twice dally for 20 minutes. Hot sitz baths will help relieve pain associated with cystitis.
  • Drink plenty of water. A six to eight ounce glass of quality water every hour is extremely beneficial for urinary tract infections.
  • Take the recommended label dosage of the Factor Eleven: CranPlex.
  • Include celery, parsley, watermelon, and cucumbers in the diet as these foods act as natural diuretics.
  • Consider a low-protein diet, obtaining protein from vegetable sources such as peas, beans, lentils and asparagus.
  • Women who suffer from recurrent bladder infections should not use tampons, and should always wear cotton underwear, never nylon.



  1. Branch, WT, Office Practice of Medicine, W.B. Saunders, Phil., PA, pp. 679-85, 1982
  2. Blumer, JL, et al., J American Medical Association, Feb 24, 1999
  3. Sternlieb,D. New England J Med, v 268, p. 57, 1963
  4. Moen, DV, Wisconsin Med J, v 61, p. 283, 1962
  5. Howel, A, et al., New England J Med., Oct 8, 1998
  6. Pizzorno, JE, et al., A textbook of Natural Medicine, Bastyr College Pub, Seattle, WA 1988
  7. Amin, AH, et al., Can. J. Microbiol, v 15, pp. 1067-76, 1969
  8. Bernstien, et al, American J Clinical Nutrition, v 30, p. 613, 1977
  9. Branch, WT, Office Practice of Medicine, W.B. Saunders, Phil, PA, pp.679-85, 1982
  10. Anton, R et al, Pharmacology, v 20 pp. 104-12, 1980
  11. Gunn, J.H. Gunn's Newest Family Physician, Philadelphia, 1878
  12. Baorto, DM & Abraham, S. Nature, Oct 9, 1997